Description

Zomepirac Sodium Salt-D4 is a deuterated analog of the non-steroidal anti-inflammatory drug (NSAID) zomepirac, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is a critical reference standard and internal standard for precise analytical quantification. It is essential for researchers and quality control laboratories in the pharmaceutical and analytical chemistry sectors who require high-fidelity standards for method development, pharmacokinetic studies, and ensuring regulatory compliance in bioanalytical assays.

Application

• Primary Use as an Internal Standard: Employed in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of zomepirac and its metabolites in biological matrices.
• Pharmacokinetic and Metabolism Research: Facilitates detailed studies on drug absorption, distribution, metabolism, and excretion (ADME) due to its near-identical chemical properties with the non-labeled compound.
• Bioanalytical Method Development and Validation: Serves as a critical component in developing robust, sensitive, and specific analytical methods compliant with FDA, EMA, and ICH guidelines.
• Pharmaceutical Quality Control: Used in impurity profiling and assay development to ensure the purity, potency, and safety of pharmaceutical products containing related compounds.
• Forensic and Clinical Toxicology: Aids in the precise detection and measurement of zomepirac in forensic investigations or clinical case studies.

Basic Information

Product Name	Zomepirac Sodium Salt-D4
CAS No.	85577-28-2
Molecular Formula	C15H10D4ClNNaO3 • xH2O
Molecular Weight	Approx. 333.74 (Anhydrous basis)
Synonyms	Zomepirac-d4 Sodium Salt; [1,4,5,8-D4]-Zomepirac Sodium Salt; 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid-d4 sodium salt; Sodium 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate-d4; Deuterated Zomepirac Sodium; Zomepirac (methyl-d4) Sodium Salt; CL-71563-d4 (sodium salt)
EINECS	Contact for details

Quality Control

Every batch of Zomepirac Sodium Salt-D4 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, MS, and HPLC. A Certificate of Analysis (COA) detailing batch-specific results for identity, purity (HPLC), isotopic enrichment, and residual solvents is provided to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to expected mass spectrum
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Enrichment	≥98.0 atom % D
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.