Description

4-Chlorotoluene-2,3,5,6-D4 is a deuterated isotopologue of 4-chlorotoluene, where four hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This deuteration is critical for applications requiring reduced metabolic interference or enhanced analytical precision, such as in the development of internal standards for mass spectrometry. It is an essential building block and analytical tool for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in GC-MS and LC-MS analysis due to its isotopic purity and similar chemical behavior to non-deuterated analogs.
• Pharmaceutical Research & Development: Serves as a deuterated precursor or intermediate in the synthesis of labeled drug candidates for pharmacokinetic, metabolic, and tracer studies.
• Agrochemical Research: Employed in the development and analysis of deuterated pesticides or herbicides to study environmental fate and metabolic pathways.
• NMR Solvent & Reagent: Acts as a deuterated solvent or shift reagent in Nuclear Magnetic Resonance (NMR) spectroscopy.
• Organic Synthesis & Catalysis Research: Utilized as a specialized reagent to investigate reaction mechanisms, kinetic isotope effects, and catalytic processes.
• Material Science: Incorporated into the synthesis of advanced organic electronic materials where isotopic labeling is used to study charge transport and stability.

Basic Information

Product Name	4-Chlorotoluene-2,3,5,6-D4
CAS No.	85577-24-8
Molecular Formula	C7H3D4Cl
Molecular Weight	131.61 g/mol
Synonyms	4-Chloro-2,3,5,6-tetradeuteriotoluene; p-Chlorotoluene-d4; 1-Chloro-4-(trideuteriomethyl)benzene-2,3,5,6-d; Toluene-d4, 4-chloro-; 4-Chlorotoluene-d4; 4-Methylchlorobenzene-d4; p-Methylchlorobenzene-d4; Deuteronated 4-Chlorotoluene
EINECS	Contact for details

Quality Control

Our 4-Chlorotoluene-2,3,5,6-D4 is produced under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical identity. Key parameters verified include isotopic enrichment (D-atom %), chemical purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing NMR, GC-MS, and HPLC results is provided with every shipment to guarantee consistency and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.