Description

(Z)-3-(1H-Indol-3-Yl)Acrylonitrile is a specialized organic compound featuring an indole core linked to an acrylonitrile moiety via a Z-configured double bond. This unique structure makes it a valuable versatile building block for synthesizing complex heterocyclic molecules and biologically active intermediates. It is primarily sought after by pharmaceutical research and agrochemical development teams for creating novel compounds with potential therapeutic or pesticidal properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based drug candidates, including potential kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the bioactivity of the indole scaffold.
• Organic Synthesis Building Block: Serves as a versatile Michael acceptor or dienophile in cycloaddition reactions for constructing complex polycyclic frameworks.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying biological pathways.

Basic Information

Product Name	(Z)-3-(1H-Indol-3-Yl)Acrylonitrile
CAS No.	85452-79-5
Molecular Formula	C11H8N2
Molecular Weight	168.20 g/mol
Synonyms	(Z)-3-(1H-Indol-3-yl)prop-2-enenitrile; (Z)-3-(Indol-3-yl)acrylonitrile; (Z)-3-(3-Indolyl)acrylonitrile; (Z)-3-(1H-Indol-3-yl)-2-propenenitrile; (Z)-Indole-3-acrylonitrile; (Z)-β-(3-Indolyl)acrylonitrile; (Z)-3-Indolylacrylonitrile; (Z)-3-(Indol-3-yl)acrylonitrile
EINECS	Contact for details

Quality Control

Our (Z)-3-(1H-Indol-3-Yl)Acrylonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.