Description

(E)-3-(1H-Indol-3-Yl)Acrylonitrile is a versatile indole-based acrylonitrile derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its conjugated structure makes it a valuable building block for constructing complex heterocyclic systems and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and plant growth regulators with enhanced activity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced photonic materials due to its electron-accepting properties.
• Fluorescent Probe Development: Serves as a core structure for synthesizing indole-based fluorescent dyes and sensors for biological imaging.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis, including cycloaddition reactions and cross-coupling protocols.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	(E)-3-(1H-Indol-3-Yl)Acrylonitrile
CAS No.	85452-78-4
Molecular Formula	C11H8N2
Molecular Weight	168.20 g/mol
Synonyms	(E)-3-(1H-Indol-3-yl)prop-2-enenitrile; trans-3-Indolylacrylonitrile; 3-(3-Indolyl)acrylonitrile; (E)-3-Indol-3-ylacrylonitrile; 2-Propenenitrile, 3-(1H-indol-3-yl)-, (2E)-; Indole-3-acrylonitrile; 3-(1H-Indol-3-yl)-2-propenenitrile
EINECS	Contact for details

Quality Control

Our (E)-3-(1H-Indol-3-Yl)Acrylonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.