Description

1-Mercaptopyrrolidin-2-One is a versatile sulfur-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a thiol and a lactam moiety, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions and asymmetric synthesis.
• Peptidomimetic Research: Core structure for designing and synthesizing peptidomimetics and protease inhibitors.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing thiol groups into polymer chains.
• Chemical Biology Probes: Utilized in the development of probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	1-Mercaptopyrrolidin-2-One
CAS No.	85443-50-1
Molecular Formula	C₄H₇NOS
Molecular Weight	117.17 g/mol
Synonyms	2-Pyrrolidinethione; 1-Thioxopyrrolidin-2-one; 2-Pyrrolidinone, 1-mercapto-; 1-Mercapto-2-pyrrolidinone; Pyrrolidine-2-thione; 1-Thioxo-2-pyrrolidinone; NSC 339586
EINECS	Contact for details

Quality Control

Our 1-Mercaptopyrrolidin-2-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.