Description

3-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethoxy substituents. This compound is essential for synthesizing advanced pharmaceutical intermediates and agrochemicals, where its unique halogenated structure imparts critical biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Science: Employed to introduce halogenated aromatic units into specialty polymers to modify thermal stability and chemical resistance.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for complex molecule assembly.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol
CAS No.	85366-65-0
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.03 g/mol
Synonyms	α-(Bromomethyl)-2-bromo-5-(trifluoromethoxy)benzene; (3-Bromo-4-(trifluoromethoxy)phenyl)methanol; 2-Bromo-α-(bromomethyl)-5-(trifluoromethoxy)benzene; 3-Bromo-4-(trifluoromethoxy)benzenemethanol; 1-Bromo-2-(hydroxymethyl)-5-(trifluoromethoxy)benzene; Benzenemethanol, 3-bromo-4-(trifluoromethoxy)-; 85366-65-0
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.