Description

1-(2-Trimethylsiloxyethoxy)-1-Trimethylsiloxy-2-Methylpropene is a specialized organosilicon compound, also known as a silyl ketene acetal, valued for its role as a versatile synthetic intermediate in advanced organic synthesis. Its primary significance lies in its ability to act as a protected enolate equivalent, enabling controlled carbon-carbon bond formation under mild conditions. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing specific molecular frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific silicon-containing motifs.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent in the development of specialty silicones and performance polymers.
• Organic Synthesis Reagent: Employed in aldol, Michael, and other nucleophilic addition reactions where a protected, thermally stable enolate is required.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance, flavor, and dye molecules.
• Research & Development: A critical tool for medicinal chemistry and process chemistry R&D in academic and industrial laboratories.

Basic Information

Product Name	1-(2-Trimethylsiloxyethoxy)-1-Trimethylsiloxy-2-Methylpropene
CAS No.	85248-36-8
Molecular Formula	C13H30O3Si2
Molecular Weight	290.55 g/mol
Synonyms	1,1-Bis(trimethylsiloxy)-2-methyl-1-(2-trimethylsiloxyethoxy)propene; 2-Methyl-1-[2-(trimethylsiloxy)ethoxy]-1-(trimethylsiloxy)-1-propene; Silyl Ketene Acetal TMS Derivative; 1-(2-Trimethylsilyloxyethoxy)-1-trimethylsilyloxy-2-methylpropene; Bis(trimethylsilyl) Ketene Acetal Ether; MTBSTFA derivative of methyl isobutyrate; (2-Methyl-1-trimethylsiloxyprop-1-enyloxy)trimethylsilane ethyl ether
EINECS	Contact for details

Quality Control

Our production of 1-(2-Trimethylsiloxyethoxy)-1-Trimethylsiloxy-2-Methylpropene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including GC, HPLC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.