Description

(S)-Methyl 1-Methyl-4,9-Dihydro-3H-Pyrido[3,4-B]Indole-3-Carboxylate Hydroiodide is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it serves as a critical building block for the development of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its role in creating novel therapeutic agents with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of complex alkaloid-based Active Pharmaceutical Ingredients (APIs).
• Neurological Drug Development: Used in the synthesis of investigational compounds targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Employed as a critical reagent in stereoselective chemical reactions to construct complex molecular architectures.
• Preclinical & Clinical Research: Serves as a starting material or intermediate for novel drug candidates in various stages of development.
• Process Chemistry: Utilized in route scouting and scale-up optimization for new pharmaceutical manufacturing processes.
• Academic Research: A valuable compound for university and institutional research in medicinal chemistry and organic synthesis.

Basic Information

Product Name	(S)-Methyl 1-Methyl-4,9-Dihydro-3H-Pyrido[3,4-B]Indole-3-Carboxylate Hydroiodide
CAS No.	85239-46-9
Molecular Formula	C15H17IN2O2
Molecular Weight	384.21 g/mol
Synonyms	(S)-1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid methyl ester hydroiodide; (S)-Methyl 1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylate hydroiodide; (S)-MTCA methyl ester hydroiodide; (S)-1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid methyl ester, hydroiodide salt; (S)-Methyl tetrahydroharmane-3-carboxylate hydroiodide
EINECS	Contact for details

Quality Control

Our (S)-Methyl 1-Methyl-4,9-Dihydro-3H-Pyrido[3,4-B]Indole-3-Carboxylate Hydroiodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.