Description

1,2-Benzenedimethanol,-α-,-α--Diethyl-,(-α-R,-α-R)-Rel-(9Ci) is a chiral diol derivative of benzene, characterized by its specific stereochemistry at the alpha positions. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, where its rigid aromatic core and defined stereocenters are critical for constructing complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications such as asymmetric catalysis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and development of advanced chiral pesticides and herbicides, where stereochemistry influences biological activity.
• Ligand and Catalyst Development: Acts as a backbone for creating chiral ligands used in asymmetric hydrogenation and other enantioselective catalytic processes.
• Specialty Polymer Monomer: Employed in the development of high-performance, optically active polymers and resins with specific thermal or mechanical properties.
• Fine Chemical Synthesis: Functions as a building block for complex fragrances, flavors, and other high-value specialty chemicals requiring precise stereochemical control.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry and material science focused on stereoselective synthesis.

Basic Information

Item	Details
Product Name	1,2-Benzenedimethanol,-α-,-α--Diethyl-,(-α-R,-α-R)-Rel-(9Ci)
CAS No.	85157-47-7
Molecular Formula	C14H22O2
Molecular Weight	222.32 g/mol
Synonyms	(R,R)-1,2-Bis(1-hydroxy-1-ethylmethyl)benzene; (R,R)-1,2-Bis(1-hydroxypropyl)benzene; (R,R)-1,2-Diethyl-1,2-benzenedimethanol; rel-(R,R)-1,2-Bis(α-hydroxypropyl)benzene; 1,2-Benzenedimethanol, α,α'-diethyl-, (R,R)-rel-; Benzene-1,2-diylbis(1-hydroxypropyl) (stereoisomer); Chiral 1,2-Benzenedimethanol Diethyl Derivative
EINECS	Contact for details

Quality Control

Our production of 1,2-Benzenedimethanol,-α-,-α--Diethyl-,(-α-R,-α-R)-Rel-(9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.