Description

(+)-B-Methoxydiisopinocampheylborane CAS NO 85134-98-1 is a highly valuable chiral organoborane reagent, specifically the (+)-enantiomer of B-methoxydiisopinocampheylborane. This compound is a cornerstone in modern asymmetric synthesis, enabling the stereoselective creation of complex molecules with high enantiomeric purity. It is an essential tool for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over stereochemistry in their synthetic routes.

Application

• Asymmetric Hydroboration: A premier reagent for the enantioselective hydroboration of prochiral alkenes, a key step in synthesizing chiral alcohols.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral building blocks and active pharmaceutical ingredients (APIs) with defined stereocenters.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Natural Product Synthesis: Facilitates the stereocontrolled total synthesis of complex natural products with biological activity.
• Chiral Auxiliary and Ligand Preparation: Serves as a precursor for other chiral reagents and catalysts used in asymmetric catalysis.
• Fine Chemical and Specialty Material Production: Enables the manufacture of high-value chiral compounds for electronics, flavors, and fragrances.

Basic Information

Product Name	(+)-B-Methoxydiisopinocampheylborane
CAS No.	85134-98-1
Molecular Formula	C₂₁H₃₇BO
Molecular Weight	304.33 g/mol
Synonyms	(+)-B-Methoxybis(3-pinanyl)borane; (+)-Methoxydiisopinocampheylborane; (+)-DIP-Chloride™ (after reaction with HCl); (1R,2R,3R,5S)-(+)-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-yl Methoxyborane(2:1); (+)-B-Methoxy-di-3-pinanylborane; Alpine Borane® (related commercial name for the hydroboration complex); (1R)-(-)-B-Methoxydiisopinocampheylborane (enantiomer)
EINECS	Contact for details

Quality Control

Every batch of (+)-B-Methoxydiisopinocampheylborane is manufactured and tested under strict quality management protocols to ensure consistent performance and enantiomeric purity. Our products undergo rigorous quality testing, including chiral analysis, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, this reagent should be handled under an inert atmosphere (argon or nitrogen) and stored with appropriate desiccants. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution or solid
Identification (NMR)	Conforms to structure
Purity (Assay)	≥ 95.0% (by NMR or Titration)
Enantiomeric Excess (ee)	≥ 98.0% (by Chiral HPLC or GC)
Solvent (if supplied as solution)	Specified (e.g., Tetrahydrofuran, Hexanes)
Concentration (if supplied as solution)	Specified (e.g., 1.0 M in THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.