Description

5-Chloro-1H-Indole-2,3-Dione 3-Oxime is a versatile and high-value synthetic intermediate belonging to the isatin oxime class of heterocyclic compounds. Its unique molecular scaffold, featuring both chloro and oxime functional groups, makes it a critical precursor for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical industry for synthesizing novel drug candidates, particularly those targeting central nervous system disorders and infectious diseases.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex molecules with potential biological activity, including kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis: Serves as a versatile precursor for constructing indole-based frameworks and other nitrogen-containing heterocycles in academic and industrial R&D.
• Material Science: Investigated for use in the synthesis of organic ligands and functional materials due to its chelating properties.

Basic Information

Product Name	5-Chloro-1H-Indole-2,3-Dione 3-Oxime
CAS No.	85124-16-9
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	5-Chloroisatin 3-oxime; 5-Chloro-2,3-dioxoindoline 3-oxime; 5-Chloro-1H-indole-2,3-dione, 3-oxime; 5-Chloro-3-hydroxyiminoisatin; 5-Chloro-3-(hydroxyimino)indolin-2-one; 85124-16-9; 5-Chloro-3-isonitrosoisatin
EINECS	Contact for details

Quality Control

Our 5-Chloro-1H-Indole-2,3-Dione 3-Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.