Description

4-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3-Iodo-1H-Indole-2-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidates, particularly those targeting neurological or cardiovascular systems.
• Biochemical Tool Compound: Serves as a probe or reference standard in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Process Development: Employed in scaling up synthetic routes for potential new drugs, aiding in route scouting and optimization.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	4-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3-Iodo-1H-Indole-2-Carbonitrile
CAS No.	85124-14-7
Molecular Formula	C16H20IN3O2
Molecular Weight	413.26 g/mol
Synonyms	3-Iodo-4-[3-[(tert-butyl)amino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile; 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-3-iodo-1H-indole-2-carbonitrile; tert-Butyl-[2-hydroxy-3-[(3-iodo-2-cyano-1H-indol-4-yl)oxy]propyl]amine; 85124-14-7; 4-(3-(tert-Butylamino)-2-hydroxypropoxy)-3-iodo-1H-indole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 4-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3-Iodo-1H-Indole-2-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.