Description

1H-Indole,2-Ethynyl-1-Methyl- is a specialized indole derivative characterized by its ethynyl and methyl substituents, which impart unique reactivity and structural properties. This compound serves as a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemical development, and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: The ethynyl group allows for further functionalization via click chemistry (e.g., Huisgen cycloaddition) and cross-coupling reactions.
• Material Science: Serves as a monomer or precursor for the development of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Biochemical Research: Used as a probe or inhibitor in enzymatic studies due to its structural similarity to biologically active indole alkaloids.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized indole-based colorants and fluorescent markers.

Basic Information

Product Name	1H-Indole,2-Ethynyl-1-Methyl-
CAS No.	85094-87-7
Molecular Formula	C11H9N
Molecular Weight	155.20 g/mol
Synonyms	2-Ethynyl-1-methyl-1H-indole; 1-Methyl-2-ethynylindole; 2-Ethynyl-1-methylindole; 1-Methyl-2-ethynyl-1H-indole; 2-Ethynyl-1-methyl-1H-indole; 1-Methyl-2-ethynyl-1H-indole; 1-Methyl-2-ethynylindole; 2-Ethynyl-1-methylindole
EINECS	Contact for details

Quality Control

Our 1H-Indole,2-Ethynyl-1-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.