Description

3-Iodo-1-Methylindole is a versatile halogenated indole derivative, a key synthetic intermediate prized for its reactivity in cross-coupling reactions. Its value lies in enabling the efficient construction of complex heterocyclic scaffolds essential for advanced material and life science research. This compound is primarily needed by pharmaceutical R&D teams, agrochemical scientists, and specialty chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators that require functionalized indole structures.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where halogenated indoles can modify electronic properties.
• Cross-Coupling Reactions: Acts as a reliable substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form carbon-carbon bonds.
• Chemical Synthesis: Employed in academic and industrial laboratories for the preparation of complex natural product analogs and other specialty indole derivatives.
• Ligand & Catalyst Development: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	3-Iodo-1-Methylindole
CAS No.	85092-84-8
Molecular Formula	C9H8IN
Molecular Weight	257.07 g/mol
Synonyms	1-Methyl-3-iodoindole; 3-Iodo-1-methyl-1H-indole; 1-Methyl-3-iodo-1H-indole; 3-Iodo-N-methylindole; 1H-Indole, 3-iodo-1-methyl-; 85092-84-8; 3-Iodo-1-methylindole
EINECS	Contact for details

Quality Control

Our 3-Iodo-1-Methylindole is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.