Description

n-Boc-2-Amino-3-Bromothiophene is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the construction of complex pharmaceutical molecules and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of thiophene-containing drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for enhanced bioactivity.
• Material Science: Serves as a precursor for conjugated polymers and organic semiconductors used in electronic devices like OLEDs and solar cells.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	n-Boc-2-Amino-3-Bromothiophene
CAS No.	85069-60-9
Molecular Formula	C9H12BrNO2S
Molecular Weight	278.17 g/mol
Synonyms	tert-Butyl (3-bromothiophen-2-yl)carbamate; 2-Amino-3-bromothiophene, N-BOC protected; N-(tert-Butoxycarbonyl)-3-bromo-2-aminothiophene; 3-Bromo-2-[(tert-butoxycarbonyl)amino]thiophene; Boc-2-Amino-3-Bromothiophene; 85069-60-9; (3-Bromothiophen-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-2-Amino-3-Bromothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.