Description

1H-Benzimidazole,1-(Difluoromethyl)-2-Methyl-(9Ci) is a specialized benzimidazole derivative distinguished by its difluoromethyl and methyl substituents, which confer unique electronic and steric properties. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzymatic pathways.
• Agrochemical Research: Used as a core scaffold for developing new fungicides, herbicides, and plant growth regulators.
• Material Science: Acts as a monomer or additive in the production of specialty polymers and advanced functional materials.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its modifiable benzimidazole core.
• Biochemical Research: Utilized as a ligand or inhibitor in biochemical assays and proteomics research.

Basic Information

Product Name	1H-Benzimidazole,1-(Difluoromethyl)-2-Methyl-(9Ci)
CAS No.	84941-16-2
Molecular Formula	C9H8F2N2
Molecular Weight	182.17 g/mol
Synonyms	1-(Difluoromethyl)-2-methyl-1H-benzimidazole; 2-Methyl-1-(difluoromethyl)benzimidazole; 1H-Benzimidazole, 1-(difluoromethyl)-2-methyl-; 84941-16-2; 1-(Difluoromethyl)-2-methylbenzimidazole; 2-Methyl-1-difluoromethylbenzimidazole; Benzimidazole, 1-(difluoromethyl)-2-methyl-
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethyl)-2-methyl-1H-benzimidazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.