Description

trans-4-(4-Bromophenyl)Cyclohexanol is a versatile brominated cyclohexanol derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the combination of a rigid cyclohexyl backbone with a para-brominated aromatic ring, enabling precise stereochemical control and facilitating further functionalization via cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of brominated compounds for liquid crystal displays (LCDs) and other advanced electronic materials.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for brominated host or transport materials in OLED device research.
• Cross-Coupling Reactions: The bromophenyl group makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Asymmetric Catalysis Research: Employed as a standard or proprietary ligand precursor in the development of chiral catalysts.

Basic Information

Product Name	trans-4-(4-Bromophenyl)Cyclohexanol
CAS No.	84892-42-2
Molecular Formula	C12H15BrO
Molecular Weight	255.15 g/mol
Synonyms	4-(4-Bromophenyl)cyclohexanol (trans-); trans-4-(p-Bromophenyl)cyclohexanol; (1r,4r)-4-(4-Bromophenyl)cyclohexan-1-ol; 4-Bromophenyl-4-hydroxycyclohexane; p-Bromophenylcyclohexanol; 84892-42-2; BRN 2208243
EINECS	Contact for details

Quality Control

Our trans-4-(4-Bromophenyl)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (trans-)	≥ 99.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.