Description

[2S,4S,(-)]-2,4-Pentanedithiol is a high-purity chiral dithiol compound, a crucial building block in asymmetric synthesis and catalysis. Its value lies in its ability to act as a bidentate ligand or a chiral auxiliary, enabling precise stereochemical control in the production of pharmaceuticals and advanced materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug development.
• Catalyst Ligand: Used as a chelating ligand in transition metal catalysis for asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Chiral Auxiliary: Employed in stereoselective organic synthesis to induce chirality in target molecules.
• Polymer Modification: Serves as a cross-linking agent or chain-transfer agent in the synthesis of specialty polymers with tailored properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and material science.
• Flavor & Fragrance Synthesis: Used in the production of chiral sulfur-containing compounds for high-value aroma chemicals.

Basic Information

Item	Details
Product Name	[2S,4S,(-)]-2,4-Pentanedithiol
CAS No.	84799-98-4
Molecular Formula	C5H12S2
Molecular Weight	136.28 g/mol
Synonyms	(2S,4S)-2,4-Pentanedithiol; (2S,4S)-2,4-Dimercaptopentane; (-)-2,4-Pentanedithiol; (2S,4S)-1,3-Dimercapto-2-methylbutane; L-2,4-Pentanedithiol; (2S,4S)-2,4-Dithiopentane; 2,4-Pentanedithiol, (2S,4S)-(-)-
EINECS	Contact for details

Quality Control

Our [2S,4S,(-)]-2,4-Pentanedithiol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.