Description

Cinchona Succirubra, Ext. CAS NO 84776-28-3 is a standardized botanical extract derived from the bark of the red cinchona tree, valued for its rich content of bioactive alkaloids such as quinine and quinidine. This extract is crucial for its pharmacological properties and serves as a key starting material for the isolation and synthesis of important therapeutic compounds. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and flavor industries seeking high-quality, natural-source ingredients.

Application

• Pharmaceutical Intermediates: Serves as a critical raw material for the production of antimalarial drugs and antiarrhythmic agents.
• Nutraceutical Formulations: Used in dietary supplements for its traditional bitter tonic properties to support digestive health.
• Flavor & Fragrance Industry: Employed as a natural bittering agent in beverages, including tonic water and bitter liqueurs.
• Analytical Reference Standards: Provides a source for the isolation of pure alkaloid standards used in laboratory testing and quality control.
• Traditional Medicine: Incorporated into herbal preparations following standardized extraction protocols.
• Research & Development: Used in biochemical and pharmacological studies to investigate the properties of cinchona alkaloids.

Basic Information

Product Name	Cinchona Succirubra, Ext.
CAS No.	84776-28-3
Molecular Formula	Complex botanical extract; primary alkaloids include C20H24N2O2 (Quinine)
Molecular Weight	Varies by alkaloid content (e.g., Quinine: 324.42 g/mol)
Synonyms	Red Cinchona Bark Extract; Cinchona succirubra bark extract; Peruvian Bark Extract; Quinine Bark Extract; Jesuits' Bark Extract; China Bark Extract; Cinchona Rubra Extract; Cinchona Extract
EINECS	Contact for details

Quality Control

Our Cinchona Succirubra Extract is produced under strict quality management systems. Each batch is tested to ensure consistent alkaloid content, purity, and absence of contaminants. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as total alkaloid assay, solvent residues, and heavy metals, supporting compliance with relevant pharmacopeial guidelines (e.g., USP, Ph. Eur.) for botanical extracts.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or heat should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Brown to reddish-brown powder or solid mass
Identification (TLC/HPLC)	Complies with standard (Presence of Quinine/Quinidine)
Assay (Total Alkaloids)	Min. 5.0% - 15.0% (Customizable)
Loss on Drying	≤ 5.0 %
Ash Content	≤ 5.0 %
Solvent Residues	Complies with ICH guidelines
Heavy Metals	≤ 10 ppm
Microbial Limits	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.