Description

3-(3,4-Dimethyl-Phenyl)-2-Mercapto-3H-Quinazolin-4-One is a specialized heterocyclic organic compound belonging to the quinazolinone class, serving as a key synthetic intermediate and active pharmaceutical ingredient (API) building block. Its molecular structure, featuring a mercapto group and a dimethylphenyl substituent, makes it a versatile precursor for developing compounds with targeted biological activity. This high-purity chemical is essential for research and production in the pharmaceutical and agrochemical industries, where precise molecular architecture is critical for efficacy.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for creating molecules with specific biological interactions.
• Organic Synthesis: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of combinatorial libraries.
• Biochemical Research: Employed as a reference standard or inhibitor in enzymatic studies due to its potential interaction with various biological targets.
• Material Science Precursor: Investigated for the synthesis of advanced organic materials, including ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	3-(3,4-Dimethyl-Phenyl)-2-Mercapto-3H-Quinazolin-4-One
CAS No.	84772-25-8
Molecular Formula	C₁₆H₁₄N₂OS
Molecular Weight	282.36 g/mol
Synonyms	3-(3,4-Dimethylphenyl)-2-sulfanylidene-1H-quinazolin-4-one; 2-Mercapto-3-(3,4-dimethylphenyl)-4(3H)-quinazolinone; 3-(3,4-Dimethylphenyl)-2-thioxo-1,2-dihydro-4(3H)-quinazolinone; 3-(3,4-Dimethylphenyl)-4-oxo-3,4-dihydroquinazoline-2(1H)-thione; 2-Thioxo-3-(3,4-dimethylphenyl)-1,2-dihydroquinazolin-4(3H)-one; 84772-25-8; Quinazolin-4-one, 3-(3,4-dimethylphenyl)-2-mercapto-
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dimethyl-Phenyl)-2-Mercapto-3H-Quinazolin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.