Description

3,4,5-Trimethoxybenzoic Acid-D9 is a high-purity, deuterium-labeled derivative of 3,4,5-trimethoxybenzoic acid, a key synthetic intermediate and analytical standard. This compound is essential for applications requiring precise internal standards in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily utilized by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and advanced organic synthesis.

Application

• As a deuterated internal standard for the quantification of 3,4,5-trimethoxybenzoic acid and related compounds in bioanalytical assays using LC-MS/MS.
• In pharmaceutical research for drug metabolism and pharmacokinetic (DMPK) studies to track absorption, distribution, metabolism, and excretion (ADME).
• For use in proteomics and metabolomics research as a stable isotope-labeled tracer in mass spectrometry-based workflows.
• As a specialized synthetic building block in the preparation of deuterium-labeled complex molecules for mechanistic studies.
• In quality control laboratories for the development and validation of analytical methods requiring high-purity reference materials.
• For academic research in organic chemistry, particularly in studies involving isotopic labeling and reaction mechanism elucidation.

Basic Information

Product Name	3,4,5-Trimethoxybenzoic Acid-D9
CAS No.	84759-05-7
Molecular Formula	C10D9H2O5
Molecular Weight	217.23 g/mol
Synonyms	Deuterated 3,4,5-Trimethoxybenzoic Acid; 3,4,5-Trimethoxybenzoic-d9 Acid; Gallic Acid Trimethyl Ether-d9; 3,4,5-Trimethoxybenzoic Acid (phenyl-d9); 3,4,5-Trimethoxybenzoic Acid (ring-d9); TMB-d9; TMBA-d9; Eudesmic Acid-d9
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxybenzoic Acid-D9 is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (D-content), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with relevant GLP and ISO 17025 standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.