Description

(E)-3-Bromo-2-Methyl-2-Propen-1-Ol CAS NO 84695-29-4 is a versatile brominated allylic alcohol building block, prized for its reactive olefin and hydroxyl functionalities. This compound is critical for introducing specific molecular frameworks in advanced synthetic pathways, enabling the creation of complex target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactive molecule construction.
• Material Science Monomer: Serves as a functional monomer or cross-linking agent in polymer chemistry for specialty resins and coatings.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to the reactive bromine atom.
• Ligand and Catalyst Preparation: Useful for synthesizing chiral ligands or metal-organic complexes for asymmetric catalysis.
• Flavor and Fragrance Intermediate: Potential precursor in the multi-step synthesis of complex aroma chemicals.

Basic Information

Product Name	(E)-3-Bromo-2-Methyl-2-Propen-1-Ol
CAS No.	84695-29-4
Molecular Formula	C4H7BrO
Molecular Weight	151.00 g/mol
Synonyms	3-Bromo-2-methyl-2-propen-1-ol; (E)-3-Bromo-2-methylprop-2-en-1-ol; 2-Methyl-3-bromo-2-propen-1-ol; trans-3-Bromo-2-methyl-2-propen-1-ol; 3-Bromo-2-methylallyl alcohol; Bromomethylbutenol; NSC 403119
EINECS	Contact for details

Quality Control

Our production of (E)-3-Bromo-2-Methyl-2-Propen-1-Ol adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Every lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Isomeric Purity ((E)-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.