Description

5-Chloro-1,3-Dihydro-1-(4-Piperidinyl)-1H-Benzimidazole-2-Thione is a high-value heterocyclic organic compound featuring a benzimidazole core functionalized with a piperidine ring and a thione group. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex molecular libraries due to its reactive thione and halogenated benzimidazole motifs.
• Biochemical Research: Acts as a research chemical for studying enzyme inhibition and receptor-ligand interactions in biochemical assays.
• Material Science Precursor: Investigated for use in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.

Basic Information

Product Name	5-Chloro-1,3-Dihydro-1-(4-Piperidinyl)-1H-Benzimidazole-2-Thione
CAS No.	84604-99-9
Molecular Formula	C₁₂H₁₄ClN₃S
Molecular Weight	267.78 g/mol
Synonyms	5-Chloro-1-(piperidin-4-yl)-1,3-dihydro-2H-benzimidazole-2-thione; 1-(4-Piperidinyl)-5-chloro-1,3-dihydro-2H-benzimidazole-2-thione; 5-Chloro-1-piperidin-4-yl-1H-benzimidazole-2(3H)-thione; 84604-99-9; 5-Chloro-1-(4-piperidinyl)-2-mercaptobenzimidazole; 5-Chloro-1-(4-piperidyl)-1,3-dihydro-2H-benzimidazole-2-thione
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,3-Dihydro-1-(4-Piperidinyl)-1H-Benzimidazole-2-Thione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.