Description

Golden Seal, Hydrastis Canadensis, Ext. CAS NO 84603-60-1 is a standardized botanical extract derived from the rhizome and roots of the *Hydrastis canadensis* plant, valued for its rich content of isoquinoline alkaloids such as berberine and hydrastine. This extract is a critical ingredient for industries requiring natural, bioactive compounds with a well-documented history of use. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and personal care sectors for its application in various formulations.

Application

• Pharmaceutical Intermediates: Used as a key starting material or active ingredient in the development of herbal medicinal products and dietary supplements.
• Nutraceutical Formulations: Incorporated into capsules, tablets, and liquid tonics for its purported wellness-supporting properties.
• Cosmetic & Personal Care: Found in skincare products like creams, serums, and ointments for its soothing and clarifying benefits.
• Traditional & Herbal Medicine: Serves as a base material for tinctures, powders, and other preparations in complementary healthcare.
• Research & Development: Supplied to laboratories for pharmacological studies, standardization, and analytical method development.
• Food & Beverage Fortification: Used in specialized functional food and beverage products, subject to regional regulatory approval.

Basic Information

Product Name	Golden Seal, Hydrastis Canadensis, Ext.
CAS No.	84603-60-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Goldenseal Extract; Hydrastis canadensis L. root extract; Hydrastis Extract; Berberine Extract (complex); Yellow Root Extract; Orange Root Extract; Ground Raspberry Extract; Eye Balm Extract
EINECS	Contact for details

Quality Control

Our Golden Seal Extract is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and purity. We provide comprehensive Certificates of Analysis (COA) that detail key parameters such as alkaloid content (e.g., berberine), heavy metals, residual solvents, and microbiological limits. Our quality systems are designed to support compliance with cGMP, ISO, and relevant pharmacopoeial standards (e.g., USP, Ph. Eur.) for botanical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	Fine Brownish-Yellow Powder
Identification (HPLC/TLC)	Complies
Assay (Total Alkaloids as Berberine)	≥ 5.0% - 10.0% (Customizable)
Loss on Drying	≤ 5.0%
Ash	≤ 5.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents	Complies with ICH Guidelines
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
E. Coli / Salmonella	Negative

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.