Description

2-Acetylbutyrolactone-13C4 is a stable isotope-labeled analog of 2-acetylbutyrolactone, where four carbon atoms are replaced with the carbon-13 isotope. This compound is essential for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway tracing using techniques like mass spectrometry and NMR. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries for drug development, metabolite identification, and environmental fate studies.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of 2-acetylbutyrolactone and related metabolites in complex biological matrices via LC-MS or GC-MS.
• In pharmaceutical research for drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic pathways and improve drug safety profiles.
• For metabolomics and proteomics research, enabling precise tracking and identification of biochemical transformations in cellular systems.
• In the development and validation of analytical methods to ensure regulatory compliance and data integrity in GLP/GMP environments.
• As a key intermediate or tracer in the synthesis of isotopically labeled complex molecules for research in medicinal chemistry and chemical biology.
• For environmental science studies investigating the degradation and fate of chemical compounds in ecosystems.

Basic Information

Product Name	2-Acetylbutyrolactone-13C4
CAS No.	84508-47-4
Molecular Formula	C613C4H8O3
Molecular Weight	~144.10 g/mol (for 13C4 labeled form)
Synonyms	2-Acetyl-γ-butyrolactone-13C4; 3-Acetyldihydro-2(3H)-furanone-13C4; 4-Acetylbutyrolactone-13C4; α-Acetyl-γ-butyrolactone-13C4; 2-Acetonyldihydro-2(3H)-furanone-13C4; 2-Acetylbutanoic acid γ-lactone-13C4; Isotopically labeled 2-acetylbutyrolactone; [13C4]-2-Acetylbutyrolactone
EINECS	Contact for details

Quality Control

Our 2-Acetylbutyrolactone-13C4 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to industry best practices for stable isotope production, ensuring reliable and consistent performance as an analytical standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Isotopic Purity (MS)	≥99% 13C4
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.