Description

3-[4-[(5-Chloro-3H-Benzoimidazol-2-Yl)Methoxy]Phenyl]-1-(4-Chloropheny L)Thiourea is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzimidazole-thiourea hybrid structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing bioactive molecules for potential applications in oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzimidazole-based drug candidates for preclinical and clinical research.
• Biochemical Research: Used as a reference standard or a probe molecule in biochemical assays to study enzyme inhibition and receptor binding activities.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at optimizing potency and selectivity of potential therapeutics.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) with targeted mechanisms of action.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs supporting outsourced drug discovery and development projects for global clients.

Basic Information

Product Name	3-[4-[(5-Chloro-3H-Benzoimidazol-2-Yl)Methoxy]Phenyl]-1-(4-Chloropheny L)Thiourea
CAS No.	84483-99-8
Molecular Formula	C21H16Cl2N4OS
Molecular Weight	443.35 g/mol
Synonyms	1-(4-Chlorophenyl)-3-[4-[(5-chloro-1H-benzimidazol-2-yl)methoxy]phenyl]thiourea; 3-[4-[(5-Chloro-1H-benzimidazol-2-yl)methoxy]phenyl]-1-(4-chlorophenyl)thiourea; 84483-99-8; Benzimidazole-thiourea derivative; 5-Chloro-2-[[4-[[(4-chlorophenyl)carbamothioyl]amino]phenoxy]methyl]-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our production of 3-[4-[(5-Chloro-3H-Benzoimidazol-2-Yl)Methoxy]Phenyl]-1-(4-Chloropheny L)Thiourea adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP guidelines for advanced intermediates and can provide material meeting specific customer specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.