Description

3,5-Methano-2H-Cyclopenta[B]Thiophen-6-Amine,Hexahydro-,(3-α-,3A-Bta-,5-α-,6-Bta-,6A-Bta-)-(9Ci) is a complex, stereochemically defined heterocyclic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct sophisticated molecular architectures with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its unique bridged structure imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or building block for novel polymers and advanced organic materials with specialized properties.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying cycloaddition reactions and the synthesis of complex polycyclic systems.

Basic Information

Product Name	3,5-Methano-2H-Cyclopenta[B]Thiophen-6-Amine,Hexahydro-,(3-α-,3A-Bta-,5-α-,6-Bta-,6A-Bta-)-(9Ci)
CAS No.	84413-27-4
Molecular Formula	C9H13NS
Molecular Weight	167.27 g/mol
Synonyms	Hexahydro-3,5-methano-2H-cyclopenta[b]thiophen-6-amine; 3,5-Methano-2H-cyclopenta[b]thiophen-6-amine, hexahydro-; (3α,3aβ,5α,6β,6aβ)-Hexahydro-3,5-methano-2H-cyclopenta[b]thiophen-6-amine; 84413-27-4; 3,5-Methano-2H-cyclopenta[b]thiophen-6-amine, hexahydro-, (3α,3aβ,5α,6β,6aβ)-; A bridged thiophene-amine derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the stringent requirements of cGMP for pharmaceutical applications and aligns with ISO quality principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for optimal stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.