Description

9H-Pyrido(3,4-B)Indole, 1,2,3,4-Tetrahydro-9-(2-(Dimethylamino)Ethyl)- 3-Methyl- is a complex heterocyclic organic compound belonging to the β-carboline alkaloid class, serving as a crucial advanced intermediate in modern pharmaceutical research and development. Its intricate fused-ring structure with a dimethylaminoethyl side chain makes it a valuable scaffold for synthesizing novel bioactive molecules targeting the central nervous system. This high-purity building block is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of potential neuroactive drugs, including serotonin receptor modulators and MAO inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to explore new pharmacophores for neurological and psychiatric disorders.
• Biochemical Tool Compound: Employed in in-vitro assays to study enzyme interactions and receptor binding mechanisms related to β-carboline pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex, polycyclic molecular architectures in custom synthesis projects.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling of related active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	9H-Pyrido(3,4-B)Indole, 1,2,3,4-Tetrahydro-9-(2-(Dimethylamino)Ethyl)- 3-Methyl-
CAS No.	84298-41-9
Molecular Formula	C18H23N3
Molecular Weight	281.40 g/mol
Synonyms	3-Methyl-9-(2-(dimethylamino)ethyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 9H-Pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-9-[2-(dimethylamino)ethyl]-3-methyl-; 3-Methyl-1,2,3,4-tetrahydro-9-(2-(dimethylamino)ethyl)-9H-pyrido[3,4-b]indole; Tetrahydro-β-carboline derivative; DMET; A β-carboline alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our 9H-Pyrido(3,4-B)Indole, 1,2,3,4-Tetrahydro-9-(2-(Dimethylamino)Ethyl)- 3-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques (HPLC, GC, NMR). We support cGMP compliance for relevant grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maximize stability, as the compound may be sensitive to oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.