Description

10-[2-(Dimethylamino)Ethyl]-5-Ethyl-5H-Dibenz[B,F]Azepine is a high-purity, advanced pharmaceutical intermediate belonging to the dibenzazepine class of compounds. This specialized chemical is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel tricyclic antidepressant and antipsychotic drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new central nervous system (CNS) active compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating neurotransmitter receptor binding and modulation.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex dibenzazepine derivatives in pilot plants.

Basic Information

Product Name	10-[2-(Dimethylamino)Ethyl]-5-Ethyl-5H-Dibenz[B,F]Azepine
CAS No.	84142-15-4
Molecular Formula	C20H24N2
Molecular Weight	292.42 g/mol
Synonyms	5-Ethyl-10-[2-(dimethylamino)ethyl]-5H-dibenz[b,f]azepine; 5-Ethyl-10-(2-dimethylaminoethyl)dibenz[b,f]azepine; Desipramine Impurity; Desmethylimipramine; G-35020; Norimipramine; Pertofrane Impurity
EINECS	Contact for details

Quality Control

Our 10-[2-(Dimethylamino)Ethyl]-5-Ethyl-5H-Dibenz[B,F]Azepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.