Description

Indole-2-Carboxylic Acid tert-Butyl Ester is a protected derivative of indole-2-carboxylic acid, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyl ester group, which provides excellent stability under various reaction conditions while allowing for selective deprotection, making it indispensable for constructing complex molecular architectures. This high-purity building block is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the indole core's bioactivity.
• Organic Synthesis & Research: Serves as a versatile precursor for generating novel indole-based compounds in academic and industrial R&D laboratories.
• Material Science: Potential monomer or intermediate for creating specialized polymers and functional organic materials.
• Chemical Biology: Employed in the development of molecular probes and biochemical tools due to its derivatizable structure.

Basic Information

Product Name	Indole-2-Carboxylic Acid tert-Butyl Ester
CAS No.	84117-86-2
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	tert-Butyl Indole-2-carboxylate; 2-(tert-Butoxycarbonyl)indole; 1H-Indole-2-carboxylic acid, 1,1-dimethylethyl ester; Indole-2-carboxylic acid t-butyl ester; 2-Carboxyindole tert-butyl ester; t-BOC-Indole-2-carboxylic acid; BOC-Indole-2-COOH
EINECS	Contact for details

Quality Control

Our Indole-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.