Description

2,3,3-Trimethyl-3H-Indole-5-Carboxylic Acid is a versatile indole derivative carboxylic acid that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized indole core, which is essential for constructing complex molecular architectures with specific biological and photophysical properties. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides with improved efficacy.
• Dye & Pigment Manufacturing: Core structure for producing advanced indole-based dyes, pigments, and optical brighteners.
• Material Science Research: Used in the development of organic semiconductors, photochromic materials, and liquid crystals.
• Biochemical Research: Serves as a standard or reagent in studying enzyme inhibition and receptor binding activities.
• Fine Chemical Production: Intermediate for synthesizing complex fragrance compounds and other high-value specialty chemicals.

Basic Information

Product Name	2,3,3-Trimethyl-3H-Indole-5-Carboxylic Acid
CAS No.	84100-84-5
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.24 g/mol
Synonyms	5-Carboxy-2,3,3-trimethylindolenine; 2,3,3-Trimethyl-5-indolecarboxylic acid; 2,3,3-Trimethylindolenine-5-carboxylic acid; 5-Carboxy-2,3,3-trimethyl-3H-indole; 3H-Indole-5-carboxylic acid, 2,3,3-trimethyl-; Fischer base-5-carboxylic acid; Trimethylindole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2,3,3-Trimethyl-3H-Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.