Description

4,5,6,7-Tetrahydrobenzofuran-4-Ol is a versatile heterocyclic compound featuring a fused tetrahydrobenzofuran structure with a hydroxyl group, serving as a valuable chiral building block and synthetic intermediate. Its unique molecular architecture makes it a critical precursor in the synthesis of complex pharmaceuticals and fine chemicals, where precise stereochemistry is paramount. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its fused ring system.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Material Science Research: Investigated as a monomer or building block for advanced polymers and functional organic materials.

Basic Information

Product Name	4,5,6,7-Tetrahydrobenzofuran-4-Ol
CAS No.	84099-58-1
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	4-Hydroxy-4,5,6,7-tetrahydrobenzofuran; 4,5,6,7-Tetrahydro-4-hydroxybenzofuran; 4-Hydroxy-4,5,6,7-tetrahydro-1-benzofuran; Tetrahydrobenzofuran-4-ol; 4,5,6,7-Tetrahydro-1-benzofuran-4-ol; 4,7-Dihydro-4-hydroxy-5H-benzofuran; 4-Ol-tetrahydrobenzofuran
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydrobenzofuran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with every shipment. We support compliance with cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.