Description

Ruscus Aculeatus, Ext. CAS NO 84012-38-4 is a standardized botanical extract derived from the Butcher's Broom plant, valued for its rich content of bioactive compounds such as ruscogenins and neoruscogenin. This extract is prized for its venotonic and vasoconstrictive properties, making it a key functional ingredient in advanced formulations. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and personal care industries for developing products that support circulatory health and skin vitality.

Application

• Pharmaceutical Formulations: Used as an active pharmaceutical ingredient (API) in oral and topical medications for chronic venous insufficiency (CVI), hemorrhoids, and varicose veins.
• Dietary Supplements & Nutraceuticals: Incorporated into capsules, tablets, and tinctures aimed at improving peripheral circulation and reducing leg swelling and discomfort.
• Cosmetics & Skincare: A functional ingredient in anti-cellulite creams, firming serums, and under-eye treatments for its vasoconstrictive and decongestant effects.
• Sports & Topical Gels: Formulated into gels and balms to alleviate muscle fatigue and promote recovery by enhancing local blood flow.
• Veterinary Products: Employed in veterinary medicine for similar circulatory support applications in companion animals.
• Research & Development: Serves as a reference standard and raw material for pharmacological studies on vascular and inflammatory pathways.

Basic Information

Product Name	Ruscus Aculeatus, Ext.
CAS No.	84012-38-4
Molecular Formula	Not Applicable (Complex Botanical Extract)
Molecular Weight	Not Applicable (Complex Botanical Extract)
Synonyms	Butcher's Broom Extract; Ruscus Aculeatus Root Extract; Box Holly Extract; Knee Holly Extract; Jew's Myrtle Extract; Sweet Broom Extract; Ruscogenins Extract; Fragon Extract
EINECS	Contact for details

Quality Control

Our Ruscus Aculeatus Extract is produced under strict quality management systems. Each batch is tested to confirm identity, purity, and the standardized content of key marker compounds like ruscogenins. We provide comprehensive Certificates of Analysis (COA) detailing assay results, heavy metals, residual solvents, and microbiological limits, ensuring compliance with relevant pharmacopeial guidelines (e.g., USP, EP) and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or heat should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Fine brown to yellowish-brown powder
Identification (HPLC/TLC)	Complies with standard
Assay (Total Ruscogenins)	Min. 5.0% - 15.0% (Customizable)
Loss on Drying	≤ 5.0%
Ash	≤ 5.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents	Meets ICH Guidelines
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
E. Coli / Salmonella	Absent

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.