Description

Dl-Alanine-2,3,3,3-D4 is a stable isotope-labeled analog of the amino acid alanine, where four hydrogen atoms are replaced by deuterium, making it an essential tool for advanced analytical and research applications. This high-purity compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for use as an internal standard, tracer, or building block in deuterated compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the precise quantification of alanine and related metabolites in complex biological matrices via LC-MS and GC-MS.
• Metabolic Pathway Tracing: Serves as a stable isotopic tracer in metabolic flux analysis and pharmacokinetic studies to track biochemical pathways.
• NMR Spectroscopy: Employed as a deuterated standard or solvent shift reference in nuclear magnetic resonance (NMR) experiments.
• Pharmaceutical Research: Acts as a key intermediate in the synthesis of deuterated drug candidates for improved metabolic stability and ADME studies.
• Biochemical Research: Utilized in enzyme kinetics studies and protein research where non-radioactive labeling is required.
• Food & Nutritional Science: Applied in research investigating amino acid metabolism, absorption, and protein turnover.

Basic Information

Product Name	Dl-Alanine-2,3,3,3-D4
CAS No.	83998-91-8
Molecular Formula	C₃H₃D₄NO₂
Molecular Weight	93.11 g/mol
Synonyms	DL-Alanine-d4; (RS)-2-Aminopropanoic-2,3,3,3-d4 acid; Alanine-2,3,3,3-d4; (±)-Alanine-d4; 2-Aminopropionic-d4 acid; Deuterated DL-Alanine; DL-α-Alanine-d4; Alanine (2,3,3,3-d4)
EINECS	Contact for details

Quality Control

Our Dl-Alanine-2,3,3,3-D4 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity by HPLC, and specific tests for identity and impurities. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.