Description

n-[2-(Mercaptomethyl)-1-Oxo-3-Phenylpropyl]Glycine Methyl Ester is a specialized organic compound featuring a unique mercaptomethyl and phenylpropyl backbone. This structure makes it a valuable key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by pharmaceutical manufacturers and contract research organizations (CROs) for the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex APIs, particularly those targeting cardiovascular and neurological conditions.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to its structural motifs.
• Peptidomimetic Synthesis: Serves as a key precursor in creating peptidomimetics for drug discovery programs.
• Bioconjugation Chemistry: The thiol (mercapto) group enables its use in site-specific bioconjugation and linker chemistry for antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Employed in the design of chemical probes to study enzyme function and biological pathways.
• Custom Synthesis: Utilized by fine chemical suppliers for custom synthesis projects requiring this specific chiral or functionalized glycine derivative.

Basic Information

Product Name	n-[2-(Mercaptomethyl)-1-Oxo-3-Phenylpropyl]Glycine Methyl Ester
CAS No.	83960-22-9
Molecular Formula	C14H17NO3S
Molecular Weight	279.35 g/mol
Synonyms	Glycine, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-, methyl ester; Methyl N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]glycinate; (2R,3S)-3-Mercapto-2-benzylmethyl-succinic acid 4-methyl ester; 83960-22-9; Mercaptomethyl Phenylpropyl Glycine Methyl Ester; ACE Inhibitor Intermediate; Thiol-containing glycine ester
EINECS	Contact for details

Quality Control

Our n-[2-(Mercaptomethyl)-1-Oxo-3-Phenylpropyl]Glycine Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and chiral purity analysis to ensure it meets the high standards required for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.