Description

4-Bromo-2-Thiophenecarboxamide is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, enabling the introduction of both thiophene and amide functionalities into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Acts as a building block for organic semiconductors, conductive polymers, and liquid crystals due to the electron-rich thiophene ring.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	4-Bromo-2-Thiophenecarboxamide
CAS No.	83933-17-9
Molecular Formula	C5H4BrNOS
Molecular Weight	206.06 g/mol
Synonyms	4-Bromothiophene-2-carboxamide; 2-Carbamoyl-4-bromothiophene; 4-Bromo-2-carbamoylthiophene; 4-Bromothiophene-2-carboxylic acid amide; 4-Bromo-thiophene-2-carboxylic acid amide; 83933-17-9; 4-Bromothiophene-2-carboxylic acid, amide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Thiophenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.