Description

1-[3-[(Aminocarbonyl)Oxy]Propyl]-5-Chloro-1,3-Dihydro-2H-Benzimidazole-2-One is a high-purity organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. Pharmaceutical manufacturers and advanced R&D laboratories need this material for its precise chemical structure, which enables the synthesis of complex, therapeutically relevant molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel benzimidazole-derived active pharmaceutical ingredients (APIs).
• Neurological Drug Research: Used in the development of compounds targeting specific receptors within the central nervous system.
• Cardiovascular Agent Synthesis: Serves as a building block for potential drugs aimed at hypertension and related conditions.
• Chemical Biology & Proteomics: Employed as a specialized scaffold or linker in the design of molecular probes and enzyme inhibitors.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry studies and novel heterocyclic compound exploration.

Basic Information

Product Name	1-[3-[(Aminocarbonyl)Oxy]Propyl]-5-Chloro-1,3-Dihydro-2H-Benzimidazole-2-One
CAS No.	83898-40-2
Molecular Formula	C11H12ClN3O3
Molecular Weight	269.68 g/mol
Synonyms	5-Chloro-1-(3-ureidopropoxy)benzimidazolin-2-one; 5-Chloro-1-(3-carbamoyloxypropyl)benzimidazol-2(3H)-one; 1-(3-Carbamoyloxypropyl)-5-chloro-2,3-dihydro-1H-benzimidazol-2-one; Urea, N-[3-[(5-chloro-2-oxo-1H-benzimidazol-1-yl)propyl]]-; UNII-2S6K628Q4K; 83898-40-2; 1-(3-Carbamoyloxypropyl)-5-chlorobenzimidazol-2-one
EINECS	Contact for details

Quality Control

Our 1-[3-[(Aminocarbonyl)Oxy]Propyl]-5-Chloro-1,3-Dihydro-2H-Benzimidazole-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.