Description

[1R-(1Alpha,2Beta,5Alpha)]-Dimethoxymethyl[[5-Methyl-2-(1-Methylvinyl)Cyclohexyl]Oxy]Silane is a specialized organosilicon compound featuring a chiral, terpene-derived cyclohexyloxy ligand. This molecular structure is significant for its role as a highly selective chiral auxiliary or ligand in asymmetric synthesis, enabling the production of enantiomerically pure intermediates. It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand or precursor for transition metal catalysts used in stereoselective hydrogenation, hydrosilylation, and cross-coupling reactions.
• Pharmaceutical Intermediates: Critical for the synthesis of enantiomerically pure drug candidates, particularly in complex natural product derivatives and therapeutic agents.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Advanced Material Precursor: Functions as a building block for chiral stationary phases in chromatography or for introducing specific stereocenters into specialty polymers and silicones.
• Organic Synthesis Reagent: Employed as a chiral protecting group or silylating agent in multi-step synthetic routes to control regio- and stereochemistry.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex, high-value chiral aroma chemicals and flavoring agents.

Basic Information

Item	Detail
Product Name	[1R-(1Alpha,2Beta,5Alpha)]-Dimethoxymethyl[[5-Methyl-2-(1-Methylvinyl)Cyclohexyl]Oxy]Silane
CAS No.	83863-58-5
Molecular Formula	C14H28O3Si
Molecular Weight	272.46 g/mol
Synonyms	(-)-Menthyl Dimethoxymethylsilyl Ether; (1R,2S,5R)-(-)-Menthyl (Dimethoxymethylsilyl) Ether; (1R,2S,5R)-2-Isopropenyl-5-methylcyclohexyl Dimethoxymethylsilyl Ether; (-)-Menthyloxy(dimethoxymethyl)silane; L-Menthyl Dimethoxymethylsilyl Ether; (1R,2S,5R)-Menthyl Dimethoxymethylsilyl Ether; Dimethoxymethyl[((1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl)oxy]silane
EINECS	Contact for details

Quality Control

Our production of [1R-(1Alpha,2Beta,5Alpha)]-Dimethoxymethyl[[5-Methyl-2-(1-Methylvinyl)Cyclohexyl]Oxy]Silane adheres to stringent quality protocols to ensure high enantiomeric excess (ee) and chemical purity, critical for sensitive asymmetric applications. Each batch is characterized by chiral HPLC, NMR, and GC analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric ratio, and impurity profiles are provided to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.