Description

4-tert-Butyl-α-Cyclopropylbenzyl Alcohol is a specialized chiral alcohol intermediate featuring a unique combination of a tert-butyl-substituted aromatic ring and a cyclopropyl group. This compound matters as a high-value building block for the synthesis of complex molecules, offering steric bulk and conformational rigidity to influence the biological activity and physical properties of target compounds. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropyl moiety can enhance metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its structure can modify thermal and optical properties.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex, long-lasting aromatic compounds.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Item	Details
Product Name	4-tert-Butyl-α-Cyclopropylbenzyl Alcohol
CAS No.	83763-25-1
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	α-Cyclopropyl-4-tert-butylbenzyl Alcohol; (4-tert-Butylphenyl)(cyclopropyl)methanol; 1-(4-tert-Butylphenyl)-1-cyclopropylmethanol; 4-(1,1-Dimethylethyl)-α-cyclopropylbenzenemethanol; p-tert-Butyl-α-cyclopropylbenzyl Alcohol; (Cyclopropyl)(4-(tert-butyl)phenyl)methanol; 83763-25-1; Benzenemethanol, α-cyclopropyl-4-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-α-Cyclopropylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.