Description

Pentanoic-3,3-D2 Acid is a deuterium-labeled isotopologue of valeric acid, where two hydrogen atoms at the 3-position are replaced with deuterium. This precise isotopic labeling makes it an indispensable tool for advanced analytical and research applications, providing a stable internal standard for mass spectrometry and enabling detailed metabolic and pharmacokinetic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, isotopically labeled compounds for method development and quality control.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in quantitative GC-MS and LC-MS analyses, particularly for the detection and measurement of valeric acid and related metabolites in complex biological matrices.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies as a tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) pathways of candidate drug molecules.
• Metabolomics and Biomarker Discovery: Enables accurate quantification in metabolic profiling studies, helping to identify disease biomarkers and understand biochemical pathways.
• Synthetic Intermediate: Acts as a deuterated building block for the synthesis of more complex labeled compounds in medicinal and organic chemistry.
• Quality Control & Method Validation: Employed in analytical laboratories to validate testing methods, ensure accuracy, and maintain compliance with regulatory standards like GLP and GMP.

Basic Information

Product Name	Pentanoic-3,3-D2 Acid
CAS No.	83741-74-6
Molecular Formula	C5H8D2O2
Molecular Weight	104.15 g/mol
Synonyms	3,3-Dideuteriovaleric Acid; [3,3-2H2]Valeric Acid; Valeric-3,3-d2 Acid; Pentanoic-3,3-d2 Acid; 1-Butanecarboxylic-3,3-d2 Acid; n-Valeric-3,3-d2 Acid; Propylacetic-3,3-d2 Acid
EINECS	Contact for details

Quality Control

Our Pentanoic-3,3-D2 Acid is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (atom % D), chemical purity by GC or HPLC, and identity confirmation. We adhere to relevant industry standards to support research and quality control under GLP/GMP frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are securely sealed and stored away from heat, sparks, and open flames. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.