Description

5,6-Difluoroisatin is a high-value fluorinated heterocyclic building block, specifically a difluoro-substituted isatin derivative. Its unique structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other bioactive molecules where the isatin core is pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides that leverage fluorinated compounds for enhanced efficacy.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic systems and fluorinated organic compounds in academic and industrial R&D.
• Material Science Research: Investigated for potential use in the development of organic electronic materials and dyes due to its conjugated structure.

Basic Information

Product Name	5,6-Difluoroisatin
CAS No.	83684-73-5
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	5,6-Difluoro-1H-indole-2,3-dione; 5,6-Difluoroindoline-2,3-dione; 5,6-Difluoro-2,3-dihydro-1H-indole-2,3-dione; 5,6-Difluorooxindole; Isatin, 5,6-difluoro-; 83684-73-5
EINECS	Contact for details

Quality Control

Our 5,6-Difluoroisatin is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.