Description

5,6,7,8-Tetrahydro-6-(Phenylmethyl)-4H-Thieno[2,3-D]Azepine-2-Carboxylic Acid, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and therapeutic agent research. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production of complex APIs containing the thienoazepine core structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	5,6,7,8-Tetrahydro-6-(Phenylmethyl)-4H-Thieno[2,3-D]Azepine-2-Carboxylic Acid, Ethyl Ester
CAS No.	83621-45-8
Molecular Formula	C19H21NO2S
Molecular Weight	327.44 g/mol
Synonyms	Ethyl 5,6,7,8-tetrahydro-6-(phenylmethyl)-4H-thieno[2,3-d]azepine-2-carboxylate; 6-Benzyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine-2-carboxylic acid ethyl ester; Thieno[2,3-d]azepine-2-carboxylic acid, 5,6,7,8-tetrahydro-6-(phenylmethyl)-, ethyl ester; 83621-45-8; Ethyl 6-benzyl-4,5,6,7-tetrahydrothieno[2,3-d]azepine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-6-(Phenylmethyl)-4H-Thieno[2,3-D]Azepine-2-Carboxylic Acid, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.