Description

3-Chloropropionic Acid, [1-14C] is a carbon-14 labeled derivative of 3-chloropropionic acid, a key building block in organic synthesis. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to track molecular pathways with high specificity. It is primarily utilized by pharmaceutical, agrochemical, and academic research institutions involved in drug development, environmental fate studies, and biochemical mechanism elucidation.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities.
• Biochemical Pathway Analysis: Serves as a radiolabeled precursor or intermediate to study specific enzymatic reactions and metabolic routes.
• Agrochemical Research: Employed in environmental fate studies to track the degradation and movement of pesticide metabolites.
• Organic Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex 14C-labeled compounds for research purposes.
• Mechanistic Studies: Facilitates the detailed investigation of reaction mechanisms in organic and medicinal chemistry.

Basic Information

Product Name	3-Chloropropionic Acid, [1-14C]
CAS No.	83565-55-3
Molecular Formula	C3H514ClO2
Molecular Weight	~108.52 (for unlabeled acid; exact mass varies with specific activity)
Synonyms	3-Chloro[1-14C]propionic Acid; [1-14C]-3-Chloropropanoic Acid; β-Chloro[1-14C]propionic Acid; 3-Chloropropanoic-1-14C Acid; NSC 8642 (labeled); 3-CPA-1-14C; Carbon-14 Labeled 3-Chloropropionic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloropropionic Acid, [1-14C] is manufactured and analyzed under strict quality control protocols to ensure high chemical and radiochemical purity. Our quality commitment includes verification of specific activity and rigorous testing to minimize radiochemical impurities. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and analytical methods (e.g., HPLC, radio-HPLC) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability. Due to its labeled nature and potential volatility, appropriate handling procedures for radioactive materials must be followed. Store in a dedicated, well-ventilated area in compliance with local radiation safety regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol range)
Solvent	Specified on label (e.g., aqueous solution, organic solvent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.