Description

1-[4-(Trifluoromethyl)Phenyl]-2-Propyn-1-Ol is a versatile fluorinated aromatic alkyne derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the trifluoromethyl group, which imparts unique electronic and lipophilic properties, making it crucial for modulating the bioactivity and stability of target molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for creating specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular reactivity and physical properties.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value fluorinated fine chemicals and specialty reagents.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]-2-Propyn-1-Ol
CAS No.	83494-26-2
Molecular Formula	C10H7F3O
Molecular Weight	200.16 g/mol
Synonyms	4-(Trifluoromethyl)phenyl propargyl alcohol; α-(Trifluoromethyl)phenylpropynyl alcohol; 1-(4-Trifluoromethylphenyl)prop-2-yn-1-ol; 1-(α,α,α-Trifluoro-p-tolyl)-2-propyn-1-ol; 4-(Trifluoromethyl)benzeneacetylene carbinol; p-(Trifluoromethyl)phenyl propargyl alcohol; 2-Propyn-1-ol, 1-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 1-[4-(Trifluoromethyl)Phenyl]-2-Propyn-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC, GC). Certificates of Analysis (COA) detailing all relevant parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.