Description

Morphine 3-Nicotinate is a specific ester derivative of morphine, where a nicotinic acid moiety is linked at the 3-hydroxy position. This compound is of significant interest in pharmaceutical research and development, particularly for studying structure-activity relationships and metabolic pathways of opioid alkaloids. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical, forensic, and analytical chemistry sectors.

Application

• Pharmaceutical Research Intermediate: Used in the synthesis and development of novel opioid receptor ligands and analgesic compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in forensic and clinical toxicology laboratories.
• Metabolic Studies: Employed in research to investigate the metabolism, pharmacokinetics, and biotransformation pathways of morphine derivatives.
• Biochemical Research: Utilized as a tool compound in studies of opioid receptor binding and signal transduction mechanisms.
• Chemical Synthesis: Acts as a key precursor for the preparation of other specialized morphine esters and related chemical entities.

Basic Information

Product Name	Morphine 3-Nicotinate
CAS No.	83465-15-0
Molecular Formula	C28H26N2O5
Molecular Weight	470.52 g/mol
Synonyms	Morphine 3-nicotinate; 3-Pyridinecarboxylic acid, (5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3-yl ester; Morphine nicotinate; Nicotinic acid morphine ester; 17-Methyl-3-nicotinoyloxymorphinan
EINECS	Contact for details

Quality Control

Our Morphine 3-Nicotinate CAS NO 83465-15-0 is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is assured through rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.