Description

5-(1-(2-Chlorophenyl)Propyl)-5,6,7,7A-Tetrahydro-4H-Thieno(3,2-C)Pyrid In-2-One Hydrochloride is a high-purity, complex heterocyclic organic compound supplied as a hydrochloride salt. This compound is of significant interest as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block in advanced research and development. It is primarily required by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new chemical entities (NCEs), particularly in neurological and psychiatric therapeutic areas.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies due to its fused thienopyridine core with a chlorophenyl substituent.
• Preclinical and Clinical Trial Material: Supplied under controlled conditions for the production of materials required for non-clinical studies and clinical trial batches.
• Reference Standard: Can be utilized as an analytical standard for method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in exploratory studies to investigate interactions with biological targets such as enzymes or receptors.

Basic Information

Product Name	5-(1-(2-Chlorophenyl)Propyl)-5,6,7,7A-Tetrahydro-4H-Thieno(3,2-C)Pyrid In-2-One Hydrochloride
CAS No.	83427-64-9
Molecular Formula	C16H18ClNO2S • HCl
Molecular Weight	360.75 g/mol
Synonyms	5-(1-(2-Chlorophenyl)propyl)-5,6,7,7a-tetrahydro-4H-thieno[3,2-c]pyridin-2-one hydrochloride; 5-(α-Propyl-2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one hydrochloride; Thieno[3,2-c]pyridin-2-one derivative hydrochloride; CAS 83427-64-9; 5-(1-(2-Chlorophenyl)propyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one HCl
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support development needs with custom purity grades and specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.