Description

2-(Methyl-D3)-1H-Imidazole is a deuterated analog of 2-methylimidazole, where three hydrogen atoms in the methyl group are replaced by deuterium. This isotopic labeling is critical for applications requiring enhanced analytical precision and metabolic stability studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled building blocks for synthesis and analysis.

Application

• As a deuterated intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Use in the development of deuterated agrochemicals to study environmental fate and metabolic pathways.
• As a precursor or catalyst modifier in specialized polymer and material science research.
• An internal standard or tracer in quantitative mass spectrometry and NMR spectroscopy for analytical method development.
• Utilization in mechanistic studies to investigate reaction pathways and isotope effects in organic synthesis.
• Potential use in the manufacturing of organic light-emitting diodes (OLEDs) and other electronic materials where deuterium substitution can improve device lifetime.

Basic Information

Product Name	2-(Methyl-D3)-1H-Imidazole
CAS No.	83413-07-4
Molecular Formula	C4H3D3N2
Molecular Weight	85.12 g/mol
Synonyms	2-(Trideuteriomethyl)-1H-imidazole; 2-Methyl-d3-imidazole; Deuterated 2-Methylimidazole; 1H-Imidazole, 2-(methyl-d3)-; 2-(Methyl-d3)imidazole; (Methyl-d3)imidazole; 2-(Trideuteromethyl)imidazole; 2-(CD3)-1H-Imidazole
EINECS	Contact for details

Quality Control

Our 2-(Methyl-D3)-1H-Imidazole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm isotopic purity, chemical purity, and identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.