Description

1-(7-Benzylidene-3-Phenyl-3,3A,4,5,6,7-Hexahydro-Indazol-2-Yl)-2-Chloro-Ethanone CAS NO 83391-21-3 is a specialized heterocyclic organic compound featuring a complex indazole core structure. This molecule is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in advanced research and development. It is primarily sought by professionals in the pharmaceutical and fine chemical sectors who require high-purity, structurally complex building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in academic and industrial R&D labs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals, dyes, or advanced material science applications.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme inhibition or receptor binding mechanisms in biological systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific indazole derivative.

Basic Information

Product Name	1-(7-Benzylidene-3-Phenyl-3,3A,4,5,6,7-Hexahydro-Indazol-2-Yl)-2-Chloro-Ethanone
CAS No.	83391-21-3
Molecular Formula	C22H19ClN2O
Molecular Weight	362.85 g/mol
Synonyms	2-Chloro-1-(7-benzylidene-3-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl)ethanone; 1-(7-Benzylidene-3-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl)-2-chloroethanone; 2-Chloro-1-(7-benzylidene-3-phenyl-2,3,3a,4,5,6,7,7a-octahydroindazol-2-yl)ethanone; Ethanone, 2-chloro-1-(7-benzylidene-3-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl)-; 83391-21-3; 7-Benzylidene-3-phenyl-3,3a,4,5,6,7-hexahydroindazol-2-yl 2-chloroethanone
EINECS	Contact for details

Quality Control

Our 1-(7-Benzylidene-3-Phenyl-3,3A,4,5,6,7-Hexahydro-Indazol-2-Yl)-2-Chloro-Ethanone is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.