Description

1,1-Bis(Iodomethyl)Cyclopropane is a specialized organoiodine compound featuring a cyclopropane ring substituted with two iodomethyl groups. This unique structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for constructing complex molecular frameworks. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications such as cyclopropanation reactions and as a precursor to other functionalized intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing cyclopropane motifs known for metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclopropane ring can enhance biological activity.
• Material Science Research: Serves as a precursor for developing specialized polymers or liquid crystals with unique thermal and optical properties.
• Cross-Coupling Reactions: Acts as an electrophilic reagent in various metal-catalyzed cross-coupling reactions (e.g., Negishi, Suzuki) to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of novel organometallic complexes and catalysts for asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological processes due to the reactivity of the iodine atoms.

Basic Information

Product Name	1,1-Bis(Iodomethyl)Cyclopropane
CAS No.	83321-23-7
Molecular Formula	C5H8I2
Molecular Weight	321.93 g/mol
Synonyms	1,1-Di(iodomethyl)cyclopropane; Cyclopropane, 1,1-bis(iodomethyl)-; Bis(iodomethyl)cyclopropane; 1,1-Bis(iodomethyl)cyclopropane; (Iodomethyl)cyclopropylmethane iodide
EINECS	Contact for details

Quality Control

Every batch of 1,1-Bis(Iodomethyl)Cyclopropane is produced and tested under stringent quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.