Description

2-Chloro-5-Methylthieno[2,3-D]Pyrimidine is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused-ring structure enables the creation of complex molecular architectures. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its thienopyrimidine core.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular scaffold or probe in biochemical research and the study of enzyme inhibitors.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-Chloro-5-Methylthieno[2,3-D]Pyrimidine
CAS No.	83259-31-8
Molecular Formula	C7H5ClN2S
Molecular Weight	184.64 g/mol
Synonyms	2-Chloro-5-methylthieno[2,3-d]pyrimidine; 5-Methyl-2-chlorothieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 2-chloro-5-methyl-; 83259-31-8; 2-Chloro-5-methyl-thieno[2,3-d]pyrimidine; 2-Chloro-5-methyl[1]benzothieno[2,3-d]pyrimidine (common misnomer); CTK8G4665; ZINC000005058761
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylthieno[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.